By Togas Tulandi, Morrie Gelfand
The topic of androgen therapy in reproductive elderly men and women is attracting expanding curiosity from experts in replica drugs, endocrinology and first care companies, in addition to from sufferers and the media.
The first publication to hide androgen alternative in males and girls, Androgens and Reproductive Aging addresses the emotive themes of reproductive getting older, the menopause and using androgen vitamins to mitigate their results.
Edited through prime specialists in reproductive drugs and infertility, and boasting an all-star solid of authors, this finished textual content covers:
* androgen construction within the fit female and male
* the decline of androgen construction in the course of getting older, with the linked results on physique composition and libido
* the advantages and capability side-effects of androgen substitute therapy.
Ideal for quite a lot of clinicians and scientists drawn to reproductive getting older, the menopause, hormone alternative and androgen treatment, in addition to obstetricians, gynecologists and family members practitioners, this specified textual content is a hugely vital addition to literature within the area.
Read or Download Androgens and Reproductive Aging PDF
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Extra resources for Androgens and Reproductive Aging
24 These observations suggest that the postmenopausal ovary as early as 5 years after menopause is not a source of androgens. 27 On the other hand, realization of the precursor role of circulating androgenic steroids leads to the prediction that lower than average levels of these steroids could lead to inadequate synthesis of estradiol in peripheral tissues such as bone and brain. 30 In addition, genetic and ethnic variation has been demonstrated in postmenopausal ovarian androgenic activity. 17,31 In defining the relationship of adrenal steroid production during declining ovarian function, Lasley et al.
Am J Physiol Endocrinol Metab 2005; 288:E775–E781. qxd 11/4/2005 2:44 PM Page 27 ENDOCRINE ASPECTS OF REPRODUCTIVE AGING 37. 38. 39. 40. 41. 42. 43. 44. 45. 46. 47. 48. 49. 50. Ravaglia G, Forti P, Maioli F et al. The relationship of dehydroepiandrosterone sulfate (DHEAS) to endocrine-metabolic parameters and functional status in the oldest-old. Results from an Italian study on healthy free-living over-ninety-year-olds. J Clin Endocrinol Metab 1996; 81:1173–1178. Hornsby PJ. Biosynthesis of DHEAS by the human adrenal cortex and its age-related decline.
27 population-based cohort of women. J Clin Endocrinol Metab 1999; 84: 4025–4030. MacNaughton J, Banah M, McCloud P, et al. Age related changes in follicle stimulating hormone, luteinizing hormone, oestradiol and immunoreactive inhibin in women of reproductive age. Clin Endocrinol 1992; 36:339–345. Sherman BM, West JH, Korenman SG. The menopausal transition: analysis of LH, FSH, estradiol, and progesterone concentrations during menstrual cycles of older women. J Clin Endocrinol Metab 1976; 42:629–636.
Androgens and Reproductive Aging by Togas Tulandi, Morrie Gelfand
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