By Jay D. Humphrey, Sherry L. O'Rourke
This ebook covers the basics of biomechanics. subject matters contain bio solids, biofluids, pressure, stability and equilibrium. scholars are inspired to contextualize rules and workouts inside of a “big photograph” of biomechanics. this is often a terrific ebook for undergraduate scholars with pursuits in biomedical engineering.
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Extra info for An Introduction to Biomechanics: Solids and Fluids, Analysis and Design
How individual molecules respond to applied loads). Zhu et al. (2000) point out, for example, that in response to applied loads, a molecule may rotate/translate, it may deform, or it may unfold/refold. By changing the conformation of a molecule, one can change its biochemical character, as, for example, the availability of binding sites. In summary then, there is a need for mechanics at all scales in biology—from the molecule to the cell to the organ to the organism. Although much is known, much remains to be discovered.
The latter must be designed based on a hypothesis or theory for the purpose of testing an idea. Because science is “relative truth,” we often need to iterate to improve our models of the physical and biological worlds. the hypothesis or theory and then to perform additional experiments and data analysis. This iterative procedure continues until the associated constitutive relation has predictive capability, which must be veriﬁed against additional observations or experimental data. , computations) and then animal and clinical trials.
5 are from Humphrey (2002). 12 1. 5 Schema of a mammalian cell showing its three primary constituents: the cell membrane (with various receptors, pumps, channels, and transmembrane proteins), the cytoplasm (including many different types of organelles, the cytoskeleton, and the cytosol), and the nucleus. From a mechanics perspective, the three primary proteins of the cytoskeleton (actin, intermediate ﬁlaments, and microtubules) are of particular importance. ]. slice of cork. Today, by the word “cell,” we mean “the fundamental, structural, and functional unit of living organisms” (Dorland’s Medical Dictionary 1988).
An Introduction to Biomechanics: Solids and Fluids, Analysis and Design by Jay D. Humphrey, Sherry L. O'Rourke
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