By Hiroshi Mitsumoto MD
This crucial publication covers each point of dwelling with ALS, from scientific good points of the ailment to an outline of symptom administration to knowing its prognosis. significant sections care for overseeing therapy and rehabilitation, dwelling with ALS, the disease’s complex section, end-of-life matters, and assets. generally revised and rewritten, this version comprises new chapters at the most up-to-date methods to treating ALS indicators, using noninvasive ventilators, multidisciplinary workforce care, new instructions being built by way of the yank Academy of Neurology for sufferers with ALS, using riluzole (Rilutek), and extra.
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Additional info for Amyotrophic Lateral Sclerosis: A Guide for Patients and Families
Rev Neurol Psychiatr. 1907;5:441–445. 40. Currier RD, Haerer AF. Amyotrophic lateral sclerosis and metallic toxins. Arch Environ Health. 1968;17:712–719. 41. Roelofs-Iverson RA, Mulder DW, Elveback LR, et al. ALS and heavy metals: a pilot case-control study. Neurology. 1984;34:393–395. 42. Boothby JA, deJesus PV, Rowland LP. Reversible forms of motor neuron disease. Arch Neurol. 1974;31:18–23. 43. Adams CR, Ziegler DK, Lin JT. Mercury intoxication simulating amyotrophic lateral sclerosis. JAMA.
DNA/RNA helicase gene mutations in a form of juvenile amyotrophic lateral sclerosis (ALS4). Am J Hum Genet. 2004;74:1128– 1135. 52. Münch C, Sedlmeier R, Meyer T, et al. Point mutations of the p150 subunit of dynactin (DCTN1) gene in ALS. Neurology. 2004;63:724–726. 53. Nishimura AL, Mitne-Neto M, Silva HC, et al. A mutation in the vesicle-trafficking protein VAPB causes late-onset spinal muscular atrophy and amyotrophic lateral sclerosis. Am J Hum Genet. 2004;75:822–831. 54. Slowik A, Tomik B, Wolkow PP, et al.
It has a single nerve fiber (axon) that extends to innervate a muscle, and it has a number of large extensions called dendrites, which branch like a tree and receive signals extensively from other neurons, including upper motor neurons and the sensory feedback system. One alpha-motoneuron innervates one group of muscle fibers, or motor unit, as discussed above. Interneurons Interneurons are small neurons in the anterior gray matter or in the brain stem motor neuron groups. They are of paramount importance in determining how the lower 28 Amyotrophic Lateral Sclerosis motor neurons control muscle contraction.
Amyotrophic Lateral Sclerosis: A Guide for Patients and Families by Hiroshi Mitsumoto MD
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